By Y. M. Dennis Lo

During this up to date moment version, top researchers practice molecular diagnostics to the numerous fresh advances that experience happened in polymerase chain response( PCR)-based applied sciences. Highlights contain real-time PCR, which permits the strategy to be played in a quantitative demeanour with better sensitivity, robustness, and resilience to carryover infection, mass spectrometric research of nucleic acids, and circulating cell-free nucleic acids in plasma. The authors practice those ideas to a huge spectrum of functions, together with gene expression, methylation, hint molecule, gene dosage, and unmarried phone research.

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Beverly Hills, CA: Sage Publications. 2 Determine a research theme and a general research question. Do preliminary readings. Elaborate a problematique. Reformulate the general research question after your preliminary readings. A thorough literature review will allow you to determine how the research theme is dealt with in the literature. Who are the principal authors? Which theories are used to discuss it? What are the principal findings? Determine the set of concepts that will be used in the observation, a set of assumptions about the relationships between them, and the set of methods to be used to conduct the observations.

The Theoretical Framework and the Specific Research Question After having completed the literature review, we have a global view of the approaches used to study a question, of the authors considered to be important, and of the major findings. We must now specify the main research question and the approach we want to adopt to study it. We will have to specify the main concepts that we are going to use and their relationships, as well as the main assumptions that underlie the research. All this constitutes the theoretical framework.

If conducted properly, this process will also allow a correct interpretation of the data produced. We will therefore examine what constitutes an acceptable process for conducting social research. There are many ways of organizing and presenting the steps of social research. But they all boil down to the same fundamental steps. We will summarize them in the following way. qxd 10/19/02 9:40 AM Page 23 THE RESEARCH PROCESS 23 Main Steps in Social Research 1. 2. 3. 4. 5. 6. 7. 8. Determine the general research question.

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