By John Timbrell
Each day we're surrounded via chemical substances which are very likely damaging. a few of these we take deliberately within the kind of medications; a few we take unknowingly in the course of the foodstuff we consume, and the surroundings round us. John Timbrell explores what makes specific chemical compounds damaging, what their results are, and the way we will be able to try for them. He examines medications resembling Paracetamol and what it does to the physique; Ricin, the main poisonous substance recognized to guy; Paraquat, a generally on hand weedkiller; and the way the puffer fish, eaten as a delicacy in Japan, can kill. utilizing case reports from all over the international, comparable to the Spanish Oil syndrome which revamped 20,000 humans sick in Madrid, Timbrell uncovers the evidence in the back of chemical scares. He indicates how, with a rational, medical, and balanced technique, hazards will be assessed and controlled competently.
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Additional resources for The Poison Paradox: Chemicals As Friends and Foes
Stopping the metabolism of the drug can increase or decrease its toxic eﬀects, depending on whether or not it is detoxiﬁed by metabolism. Because of the concentrations necessary, inhibition is most likely to be caused by drugs although some naturally occurring substances in foods,2 industrial exposure to solvents, and exposure of agricultural workers to pesticides have been shown to be at high enough levels to inhibit enzymes (see case notes). A similar example which has been known about for a long time is the so-called cheese reaction which can occur in patients taking CASE NOTES Fatal juice A young man, just 29 years old, had been taking the antihistamine drug terfenadine twice daily for two years because he suffered from hay fever.
These waste products result from normal metabolic processes but need to be eliminated. This selective loss ensures that potentially noxious and unwanted chemical substances, including natural waste products, are eliminated relatively quickly and eﬃciently, while most of the essential substances are retained. Water is one essential substance that is partly lost which has to be replaced along with salts. The function of the kidney decreases with age, and in the elderly the ability to excrete substances is reduced.
The chemical may cause an eﬀect or even damage at low doses but this may not be detectable until some function is compromised. The dose of a chemical is crucial to the toxicity because all chemicals are potentially toxic. It is simply a matter of the dose—the Paracelsus Principle. As the dose level rises, the cells or systems in the body (human or other animal) show an increasing level of dysfunction and damage. For example, if diﬀerent doses of a drug that lowers the blood pressure are given to a patient and the eﬀects on blood pressure are measured, as the dose is increased the decrease in blood pressure will increase.