By John Timbrell

Each day we're surrounded via chemical substances which are very likely damaging. a few of these we take deliberately within the kind of medications; a few we take unknowingly in the course of the foodstuff we consume, and the surroundings round us. John Timbrell explores what makes specific chemical compounds damaging, what their results are, and the way we will be able to try for them. He examines medications resembling Paracetamol and what it does to the physique; Ricin, the main poisonous substance recognized to guy; Paraquat, a generally on hand weedkiller; and the way the puffer fish, eaten as a delicacy in Japan, can kill. utilizing case reports from all over the international, comparable to the Spanish Oil syndrome which revamped 20,000 humans sick in Madrid, Timbrell uncovers the evidence in the back of chemical scares. He indicates how, with a rational, medical, and balanced technique, hazards will be assessed and controlled competently.

Show description

Read Online or Download The Poison Paradox: Chemicals As Friends and Foes PDF

Similar biology & life sciences books

Diffusion Processes and Related Topics in Biology

Those notes are in line with a one-quarter path given on the division of Biophysics and Theoretical Biology of the collage of Chicago in 1916. The path was once directed to graduate scholars within the department of organic Sciences with pursuits in inhabitants biology and neurobiology. just a mild acquaintance with likelihood and differential equations is needed of the reader.

Biomedical Aspects of the Laser: The Introduction of Laser Applications Into Biology and Medicine

This booklet is a evaluation of earlier and present reports and destiny plans of the Laser Laboratory in Cincinnati and a few of the contributions of laser learn teams in different scientific facilities. distinct thank you are a result of Directing Physicist of the Laser Labora­ tory, R. James Rockwell. with out his recommendation, consistent supervision and corrections, this enthusiastic investigator could proceed to disenchanted even many extra humans than he has performed already.

Recent Advances in Polyphenol Research Volume 2

Fresh Advances in Polyphenol ResearchVolume 2Edited via Santos-Buelga, Escribano-Bailon and LattanzioPlant phenolics are secondary metabolites that represent probably the most universal and frequent teams of drugs in vegetation. Polyphenols have a wide and numerous array of worthwhile results on either crops and animals.

Additional resources for The Poison Paradox: Chemicals As Friends and Foes

Sample text

Stopping the metabolism of the drug can increase or decrease its toxic effects, depending on whether or not it is detoxified by metabolism. Because of the concentrations necessary, inhibition is most likely to be caused by drugs although some naturally occurring substances in foods,2 industrial exposure to solvents, and exposure of agricultural workers to pesticides have been shown to be at high enough levels to inhibit enzymes (see case notes). A similar example which has been known about for a long time is the so-called cheese reaction which can occur in patients taking CASE NOTES Fatal juice A young man, just 29 years old, had been taking the antihistamine drug terfenadine twice daily for two years because he suffered from hay fever.

These waste products result from normal metabolic processes but need to be eliminated. This selective loss ensures that potentially noxious and unwanted chemical substances, including natural waste products, are eliminated relatively quickly and efficiently, while most of the essential substances are retained. Water is one essential substance that is partly lost which has to be replaced along with salts. The function of the kidney decreases with age, and in the elderly the ability to excrete substances is reduced.

The chemical may cause an effect or even damage at low doses but this may not be detectable until some function is compromised. The dose of a chemical is crucial to the toxicity because all chemicals are potentially toxic. It is simply a matter of the dose—the Paracelsus Principle. As the dose level rises, the cells or systems in the body (human or other animal) show an increasing level of dysfunction and damage. For example, if different doses of a drug that lowers the blood pressure are given to a patient and the effects on blood pressure are measured, as the dose is increased the decrease in blood pressure will increase.

Download PDF sample

Rated 4.10 of 5 – based on 26 votes